BRD-A10523515_GSK-429286A_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-A10523515_GSK-429286A_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
CCND2 cyclin D2
CDC25B cell division cycle 25B
CDH3 cadherin 3, type 1, P-cadherin (placental)
CXCL10 chemokine (C-X-C motif) ligand 10
FXYD3 FXYD domain containing ion transport regulator 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLF5 Kruppel-like factor 5 (intestinal)
LYN LYN proto-oncogene, Src family tyrosine kinase
NRN1 neuritin 1
PPAP2B phosphatidic acid phosphatase type 2B
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SOX11 SRY (sex determining region Y)-box 11
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ALCAM activated leukocyte cell adhesion molecule
CTGF connective tissue growth factor
IGFBP7 insulin-like growth factor binding protein 7
MCAM melanoma cell adhesion molecule
MYLK myosin light chain kinase
PLAU plasminogen activator, urokinase
PXDN peroxidasin
TAGLN transgelin
TPM1 tropomyosin 1 (alpha)