BRD-A10523515_GSK-429286A_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A10523515_GSK-429286A_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
C3 complement component 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
FOSL2 FOS-like antigen 2
GLRX glutaredoxin (thioltransferase)
KRT19 keratin 19, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMO2 LIM domain only 2 (rhombotin-like 1)
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MYOF myoferlin
NFE2L2 nuclear factor, erythroid 2-like 2
NID2 nidogen 2 (osteonidogen)
NKG7 natural killer cell granule protein 7
NNMT nicotinamide N-methyltransferase
PGD phosphogluconate dehydrogenase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
S100A4 S100 calcium binding protein A4
SGK1 serum/glucocorticoid regulated kinase 1
SIDT2 SID1 transmembrane family, member 2
SPTBN1 spectrin, beta, non-erythrocytic 1
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TGM2 transglutaminase 2
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
BPHL biphenyl hydrolase-like (serine hydrolase)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DIO1 deiodinase, iodothyronine, type I
DMD dystrophin
EBP emopamil binding protein (sterol isomerase)
EPHA3 EPH receptor A3
FABP1 fatty acid binding protein 1, liver
FSCN1 fascin actin-bundling protein 1
FST follistatin
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGL immunoglobulin lambda locus
IL17RB interleukin 17 receptor B
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MAP7 microtubule-associated protein 7
MFSD10 major facilitator superfamily domain containing 10
MOXD1 monooxygenase, DBH-like 1
MYBPC1 myosin binding protein C, slow type
NFIB nuclear factor I/B
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEBP1 phosphatidylethanolamine binding protein 1
PEG10 paternally expressed 10
PLAGL1 pleiomorphic adenoma gene-like 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
QKI QKI, KH domain containing, RNA binding
QPRT quinolinate phosphoribosyltransferase
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHB Src homology 2 domain containing adaptor protein B
SNX7 sorting nexin 7
TBX3 T-box 3
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb