BRD-A10330754_7815359_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A10330754_7815359_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ASCL1 achaete-scute family bHLH transcription factor 1
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CALML4 calmodulin-like 4
CAV1 caveolin 1, caveolae protein, 22kDa
CPB1 carboxypeptidase B1 (tissue)
CSTA cystatin A (stefin A)
CXCL13 chemokine (C-X-C motif) ligand 13
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLK1 delta-like 1 homolog (Drosophila)
DMXL2 Dmx-like 2
FGG fibrinogen gamma chain
GLIPR1 GLI pathogenesis-related 1
H2AFZ H2A histone family, member Z
HAL histidine ammonia-lyase
HCAR3 hydroxycarboxylic acid receptor 3
HMGB2 high mobility group box 2
HOXB7 homeobox B7
IGFBP5 insulin-like growth factor binding protein 5
KRT15 keratin 15, type I
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MXI1 MAX interactor 1, dimerization protein
NGRN neugrin, neurite outgrowth associated
NPTX2 neuronal pentraxin II
NRIP1 nuclear receptor interacting protein 1
PRAME preferentially expressed antigen in melanoma
PTHLH parathyroid hormone-like hormone
SAP30 Sin3A-associated protein, 30kDa
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TLR4 toll-like receptor 4
TSPAN7 tetraspanin 7
VNN1 vanin 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ASPN asporin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL7B B-cell CLL/lymphoma 7B
CHL1 cell adhesion molecule L1-like
CLDN3 claudin 3
CLDN4 claudin 4
CLIC4 chloride intracellular channel 4
CLTC clathrin, heavy chain (Hc)
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CXCR4 chemokine (C-X-C motif) receptor 4
DOCK4 dedicator of cytokinesis 4
EFNB2 ephrin-B2
EIF5A eukaryotic translation initiation factor 5A
ESR1 estrogen receptor 1
FAP fibroblast activation protein, alpha
FGF13 fibroblast growth factor 13
HPCAL1 hippocalcin-like 1
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
KRT7 keratin 7, type II
MAP7 microtubule-associated protein 7
MFAP5 microfibrillar associated protein 5
MMP11 matrix metallopeptidase 11
MMP7 matrix metallopeptidase 7
MUC16 mucin 16, cell surface associated
OSBPL10 oxysterol binding protein-like 10
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PMP22 peripheral myelin protein 22
PRDX2 peroxiredoxin 2
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SFTPC surfactant protein C
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SOX9 SRY (sex determining region Y)-box 9
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TACSTD2 tumor-associated calcium signal transducer 2
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TRIB2 tribbles pseudokinase 2
TRPS1 trichorhinophalangeal syndrome I
TXNDC9 thioredoxin domain containing 9
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF264 zinc finger protein 264