BRD-A10188456_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A10188456_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD59 CD59 molecule, complement regulatory protein
EFNB2 ephrin-B2
EPCAM epithelial cell adhesion molecule
F12 coagulation factor XII (Hageman factor)
GPX3 glutathione peroxidase 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP6 insulin-like growth factor binding protein 6
INSIG1 insulin induced gene 1
LTBP3 latent transforming growth factor beta binding protein 3
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANOS1 anosmin 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPN asporin
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
FGL2 fibrinogen-like 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXD1 homeobox D1
HTRA1 HtrA serine peptidase 1
IFI44 interferon-induced protein 44
LMO3 LIM domain only 3 (rhombotin-like 2)
MN1 meningioma (disrupted in balanced translocation) 1
MX1 MX dynamin-like GTPase 1
NUAK1 NUAK family, SNF1-like kinase, 1
PPOX protoporphyrinogen oxidase
SELENBP1 selenium binding protein 1
SNAI2 snail family zinc finger 2
SULF1 sulfatase 1
THBS2 thrombospondin 2