BRD-A09984573_CD 01333_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-A09984573_CD 01333_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANG angiogenin, ribonuclease, RNase A family, 5
APLP2 amyloid beta (A4) precursor-like protein 2
AQP3 aquaporin 3 (Gill blood group)
CBR3 carbonyl reductase 3
CD9 CD9 molecule
CHI3L2 chitinase 3-like 2
CLEC3B C-type lectin domain family 3, member B
COCH cochlin
DAXX death-domain associated protein
DEFB1 defensin, beta 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DSG2 desmoglein 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F2RL1 coagulation factor II (thrombin) receptor-like 1
GCLM glutamate-cysteine ligase, modifier subunit
GSTO1 glutathione S-transferase omega 1
HHLA3 HERV-H LTR-associating 3
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHM immunoglobulin heavy constant mu
ITM2A integral membrane protein 2A
KIF5C kinesin family member 5C
LBH limb bud and heart development
LGALS3 lectin, galactoside-binding, soluble, 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MFAP3L microfibrillar-associated protein 3-like
MICB MHC class I polypeptide-related sequence B
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRN1 neuritin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIR pirin (iron-binding nuclear protein)
PSD3 pleckstrin and Sec7 domain containing 3
RNASE4 ribonuclease, RNase A family, 4
RPA3 replication protein A3, 14kDa
S100A2 S100 calcium binding protein A2
SAP30 Sin3A-associated protein, 30kDa
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
TM4SF1 transmembrane 4 L six family member 1
TSPAN7 tetraspanin 7
UGDH UDP-glucose 6-dehydrogenase
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
APP amyloid beta (A4) precursor protein
ARMCX1 armadillo repeat containing, X-linked 1
ASCL1 achaete-scute family bHLH transcription factor 1
BAX BCL2-associated X protein
CD24 CD24 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHGB chromogranin B
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL5A1 collagen, type V, alpha 1
COL8A2 collagen, type VIII, alpha 2
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
DPP4 dipeptidyl-peptidase 4
DPYSL3 dihydropyrimidinase-like 3
EDNRA endothelin receptor type A
FBLN1 fibulin 1
FBN2 fibrillin 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FSTL1 follistatin-like 1
G0S2 G0/G1 switch 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LAMP5 lysosomal-associated membrane protein family, member 5
LPIN1 lipin 1
LRRC15 leucine rich repeat containing 15
LRRC17 leucine rich repeat containing 17
MFAP2 microfibrillar-associated protein 2
NEFH neurofilament, heavy polypeptide
NR2F1 nuclear receptor subfamily 2, group F, member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PXDN peroxidasin
RFTN1 raftlin, lipid raft linker 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SULF1 sulfatase 1
TGFB3 transforming growth factor, beta 3
TMEM176B transmembrane protein 176B
TSPAN8 tetraspanin 8
TTC39A tetratricopeptide repeat domain 39A
VCAN versican
ZNF589 zinc finger protein 589