BRD-A09828896_SKF 81297 hydrobromide_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-A09828896_SKF 81297 hydrobromide_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ASS1 argininosuccinate synthase 1
C3 complement component 3
CD14 CD14 molecule
CD24 CD24 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRISP3 cysteine-rich secretory protein 3
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
EDNRA endothelin receptor type A
EMX2 empty spiracles homeobox 2
FAM69A family with sequence similarity 69, member A
LBP lipopolysaccharide binding protein
MAP7 microtubule-associated protein 7
MFAP5 microfibrillar associated protein 5
NNMT nicotinamide N-methyltransferase
PDE4B phosphodiesterase 4B, cAMP-specific
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RGS2 regulator of G-protein signaling 2
SCGB2A2 secretoglobin, family 2A, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SIRPA signal-regulatory protein alpha
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SST somatostatin
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
ANXA5 annexin A5
BAG3 BCL2-associated athanogene 3
COCH cochlin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DUSP14 dual specificity phosphatase 14
EIF6 eukaryotic translation initiation factor 6
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGF13 fibroblast growth factor 13
HES1 hes family bHLH transcription factor 1
NEFL neurofilament, light polypeptide
PLAC8 placenta-specific 8
PSIP1 PC4 and SFRS1 interacting protein 1
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
XK X-linked Kx blood group
XPO7 exportin 7