BRD-A09539288_HOMATROPINE BROMIDE_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-A09539288_HOMATROPINE BROMIDE_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
ATM ATM serine/threonine kinase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CFLAR CASP8 and FADD-like apoptosis regulator
CLCA2 chloride channel accessory 2
COG7 component of oligomeric golgi complex 7
CSTA cystatin A (stefin A)
CTNND1 catenin (cadherin-associated protein), delta 1
EHBP1 EH domain binding protein 1
EXT1 exostosin glycosyltransferase 1
FKBP4 FK506 binding protein 4, 59kDa
HEG1 heart development protein with EGF-like domains 1
HIST1H2AC histone cluster 1, H2ac
IFNAR1 interferon (alpha, beta and omega) receptor 1
ITGA6 integrin, alpha 6
JAG1 jagged 1
KRT6A keratin 6A, type II
LIMCH1 LIM and calponin homology domains 1
LPAR6 lysophosphatidic acid receptor 6
MALL mal, T-cell differentiation protein-like
MAOA monoamine oxidase A
MEST mesoderm specific transcript
MPHOSPH8 M-phase phosphoprotein 8
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NID1 nidogen 1
OSBPL10 oxysterol binding protein-like 10
PEG3 paternally expressed 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PMM2 phosphomannomutase 2
PODXL podocalyxin-like
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
RAI14 retinoic acid induced 14
RGS5 regulator of G-protein signaling 5
RNF167 ring finger protein 167
SCPEP1 serine carboxypeptidase 1
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFTPD surfactant protein D
SGK1 serum/glucocorticoid regulated kinase 1
SHB Src homology 2 domain containing adaptor protein B
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1B small proline-rich protein 1B
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
APOD apolipoprotein D
BASP1 brain abundant, membrane attached signal protein 1
C6ORF62 chromosome 6 open reading frame 62
CBR3 carbonyl reductase 3
CDC42 cell division cycle 42
CLU clusterin
CXCL14 chemokine (C-X-C motif) ligand 14
CYBA cytochrome b-245, alpha polypeptide
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF4B eukaryotic translation initiation factor 4B
GPM6B glycoprotein M6B
LAGE3 L antigen family, member 3
MRPS30 mitochondrial ribosomal protein S30
NTS neurotensin
PAQR3 progestin and adipoQ receptor family member III
PCDH9 protocadherin 9
RCAN1 regulator of calcineurin 1
RPL37A ribosomal protein L37a
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK1 serine peptidase inhibitor, Kazal type 1
STOM stomatin
TM4SF4 transmembrane 4 L six family member 4
TOB1 transducer of ERBB2, 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGCG UDP-glucose ceramide glucosyltransferase
WIF1 WNT inhibitory factor 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1