BRD-A09533288_VERAPAMIL HYDROCHLORIDE_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A09533288_VERAPAMIL HYDROCHLORIDE_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AMACR alpha-methylacyl-CoA racemase
CH25H cholesterol 25-hydroxylase
CHL1 cell adhesion molecule L1-like
CPVL carboxypeptidase, vitellogenic-like
CST3 cystatin C
DHCR24 24-dehydrocholesterol reductase
FAS Fas cell surface death receptor
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GJA1 gap junction protein, alpha 1, 43kDa
HEBP1 heme binding protein 1
HP haptoglobin
IFRD2 interferon-related developmental regulator 2
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LTF lactotransferrin
PURA purine-rich element binding protein A
RAB40B RAB40B, member RAS oncogene family
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPA2 surfactant protein A2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ARL4C ADP-ribosylation factor-like 4C
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
CD52 CD52 molecule
CD69 CD69 molecule
CPM carboxypeptidase M
CRABP1 cellular retinoic acid binding protein 1
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CXCL11 chemokine (C-X-C motif) ligand 11
CYR61 cysteine-rich, angiogenic inducer, 61
DOCK4 dedicator of cytokinesis 4
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
FKBP1A FK506 binding protein 1A, 12kDa
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IER3 immediate early response 3
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LGALS1 lectin, galactoside-binding, soluble, 1
LUM lumican
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
ODC1 ornithine decarboxylase 1
PAPD7 PAP associated domain containing 7
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAU plasminogen activator, urokinase
PRNP prion protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
SCGB1D2 secretoglobin, family 1D, member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a
TUBB2B tubulin, beta 2B class IIb
VCAM1 vascular cell adhesion molecule 1
VTCN1 V-set domain containing T cell activation inhibitor 1