BRD-A09164687_1495-0136_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

147 genes differentially expressed following the BRD-A09164687_1495-0136_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AGR2 anterior gradient 2
AKAP7 A kinase (PRKA) anchor protein 7
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BACE2 beta-site APP-cleaving enzyme 2
BAMBI BMP and activin membrane-bound inhibitor
BLVRB biliverdin reductase B
CA12 carbonic anhydrase XII
CD59 CD59 molecule, complement regulatory protein
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CST3 cystatin C
CSTA cystatin A (stefin A)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
FOLR1 folate receptor 1 (adult)
FUCA1 fucosidase, alpha-L- 1, tissue
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPX2 glutathione peroxidase 2
HOXC6 homeobox C6
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KLF4 Kruppel-like factor 4 (gut)
KRT10 keratin 10, type I
LRP10 low density lipoprotein receptor-related protein 10
MBOAT7 membrane bound O-acyltransferase domain containing 7
MUC5B mucin 5B, oligomeric mucus/gel-forming
NQO1 NAD(P)H dehydrogenase, quinone 1
NRN1 neuritin 1
PRKCZ protein kinase C, zeta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPL36 ribosomal protein L36
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC44A4 solute carrier family 44, member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TRIM16 tripartite motif containing 16
TSPAN13 tetraspanin 13
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
WBSCR22 Williams Beuren syndrome chromosome region 22

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACKR3 atypical chemokine receptor 3
ADGRF5 adhesion G protein-coupled receptor F5
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANGPTL2 angiopoietin-like 2
ANK2 ankyrin 2, neuronal
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
ASPN asporin
BEX4 brain expressed, X-linked 4
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CECR1 cat eye syndrome chromosome region, candidate 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
COL8A2 collagen, type VIII, alpha 2
CORO1A coronin, actin binding protein, 1A
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
DCHS1 dachsous cadherin-related 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPYSL3 dihydropyrimidinase-like 3
EFHD1 EF-hand domain family, member D1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FILIP1L filamin A interacting protein 1-like
FNBP1 formin binding protein 1
FST follistatin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPM6B glycoprotein M6B
GUSBP11 glucuronidase, beta pseudogene 11
HTRA1 HtrA serine peptidase 1
IFI16 interferon, gamma-inducible protein 16
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
JAM3 junctional adhesion molecule 3
JCHAIN joining chain of multimeric IgA and IgM
KLF9 Kruppel-like factor 9
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MEF2C myocyte enhancer factor 2C
MEIS2 Meis homeobox 2
MFAP2 microfibrillar-associated protein 2
MME membrane metallo-endopeptidase
MZB1 marginal zone B and B1 cell-specific protein
NID1 nidogen 1
P3H2 prolyl 3-hydroxylase 2
PBX3 pre-B-cell leukemia homeobox 3
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLVAP plasmalemma vesicle associated protein
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RGS5 regulator of G-protein signaling 5
RTN2 reticulon 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCG2 secretogranin II
SGCE sarcoglycan, epsilon
SLC38A1 solute carrier family 38, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
STON1 stonin 1
SULF1 sulfatase 1
TEK TEK tyrosine kinase, endothelial
THBS2 thrombospondin 2
TSPAN12 tetraspanin 12
VTCN1 V-set domain containing T cell activation inhibitor 1
WLS wntless Wnt ligand secretion mediator
XIST X inactive specific transcript (non-protein coding)
ZMIZ1 zinc finger, MIZ-type containing 1