BRD-A09062839_Amyleine hydrochloride_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

74 genes differentially expressed following the BRD-A09062839_Amyleine hydrochloride_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BASP1 brain abundant, membrane attached signal protein 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPG capping protein (actin filament), gelsolin-like
CCL5 chemokine (C-C motif) ligand 5
CXCL13 chemokine (C-X-C motif) ligand 13
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPP4 dipeptidyl-peptidase 4
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GLRX glutaredoxin (thioltransferase)
HOPX HOP homeobox
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KRT6A keratin 6A, type II
LYZ lysozyme
MED24 mediator complex subunit 24
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NT5DC2 5'-nucleotidase domain containing 2
PLXDC1 plexin domain containing 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SOX11 SRY (sex determining region Y)-box 11
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TLK2 tousled-like kinase 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
ATF3 activating transcription factor 3
BEX4 brain expressed, X-linked 4
CCNE2 cyclin E2
CD24 CD24 molecule
CFH complement factor H
CLU clusterin
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
CXCL12 chemokine (C-X-C motif) ligand 12
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFB1 defensin, beta 1
DUSP22 dual specificity phosphatase 22
GREM1 gremlin 1, DAN family BMP antagonist
GSTM3 glutathione S-transferase mu 3 (brain)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IFRD2 interferon-related developmental regulator 2
IL1R1 interleukin 1 receptor, type I
JCHAIN joining chain of multimeric IgA and IgM
LYPD1 LY6/PLAUR domain containing 1
MOK MOK protein kinase
MSLN mesothelin
MUC16 mucin 16, cell surface associated
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
OGDHL oxoglutarate dehydrogenase-like
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEG10 paternally expressed 10
PLK1 polo-like kinase 1
PRKCI protein kinase C, iota
PSPH phosphoserine phosphatase
SGCE sarcoglycan, epsilon
SGK1 serum/glucocorticoid regulated kinase 1
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
USP22 ubiquitin specific peptidase 22