BRD-A09062839_Amyleine hydrochloride_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

75 genes differentially expressed following the BRD-A09062839_Amyleine hydrochloride_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AQP1 aquaporin 1 (Colton blood group)
C3 complement component 3
CLIC4 chloride intracellular channel 4
COPA coatomer protein complex, subunit alpha
CPM carboxypeptidase M
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FAM198B family with sequence similarity 198, member B
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
FOXO1 forkhead box O1
FZD5 frizzled class receptor 5
GATA2 GATA binding protein 2
HSPG2 heparan sulfate proteoglycan 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL13RA2 interleukin 13 receptor, alpha 2
IRS2 insulin receptor substrate 2
ITGA6 integrin, alpha 6
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NELL2 NEL-like 2 (chicken)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRNP prion protein
PRUNE2 prune homolog 2 (Drosophila)
PTCH1 patched 1
RAD23B RAD23 homolog B (S. cerevisiae)
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SORBS2 sorbin and SH3 domain containing 2
STEAP3 STEAP family member 3, metalloreductase
STOM stomatin
SYBU syntabulin (syntaxin-interacting)
TCTA T-cell leukemia translocation altered
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
THBS1 thrombospondin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABI1 abl-interactor 1
ADD3 adducin 3 (gamma)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BEX1 brain expressed, X-linked 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BZW2 basic leucine zipper and W2 domains 2
CDC123 cell division cycle 123
COMMD3 COMM domain containing 3
CYBA cytochrome b-245, alpha polypeptide
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
EPN2 epsin 2
G0S2 G0/G1 switch 2
GREM1 gremlin 1, DAN family BMP antagonist
HSPA14 heat shock 70kDa protein 14
IDI1 isopentenyl-diphosphate delta isomerase 1
IGKV4-1 immunoglobulin kappa variable 4-1
LYPD1 LY6/PLAUR domain containing 1
MSRB2 methionine sulfoxide reductase B2
PARD3 par-3 family cell polarity regulator
PROM1 prominin 1
PRPF18 pre-mRNA processing factor 18
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RRAGD Ras-related GTP binding D
S100A8 S100 calcium binding protein A8
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
YME1L1 YME1-like 1 ATPase