BRD-A09062839_Amyleine hydrochloride_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A09062839_Amyleine hydrochloride_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ANKRD10 ankyrin repeat domain 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CD40 CD40 molecule, TNF receptor superfamily member 5
CENPE centromere protein E, 312kDa
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL6A2 collagen, type VI, alpha 2
CXCL9 chemokine (C-X-C motif) ligand 9
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GRB7 growth factor receptor-bound protein 7
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
MAPT microtubule-associated protein tau
MSMB microseminoprotein, beta-
NID2 nidogen 2 (osteonidogen)
NME4 NME/NM23 nucleoside diphosphate kinase 4
NR1H2 nuclear receptor subfamily 1, group H, member 2
PAM peptidylglycine alpha-amidating monooxygenase
PLXND1 plexin D1
PPAP2B phosphatidic acid phosphatase type 2B
RPS4Y1 ribosomal protein S4, Y-linked 1
TFF1 trefoil factor 1
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNS1 tensin 1
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ANXA7 annexin A7
BST2 bone marrow stromal cell antigen 2
CD69 CD69 molecule
CLU clusterin
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
FBLN1 fibulin 1
FNTA farnesyltransferase, CAAX box, alpha
GATA6 GATA binding protein 6
GSTM3 glutathione S-transferase mu 3 (brain)
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
LRRN3 leucine rich repeat neuronal 3
LYPD1 LY6/PLAUR domain containing 1
LYRM1 LYR motif containing 1
MDK midkine (neurite growth-promoting factor 2)
MECOM MDS1 and EVI1 complex locus
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIR22HG MIR22 host gene
NQO1 NAD(P)H dehydrogenase, quinone 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
QPRT quinolinate phosphoribosyltransferase
RBP1 retinol binding protein 1, cellular
RBP4 retinol binding protein 4, plasma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPA3 replication protein A3, 14kDa
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SKP1 S-phase kinase-associated protein 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPON1 spondin 1, extracellular matrix protein