BRD-A09056319_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A09056319_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
CADM1 cell adhesion molecule 1
CD8A CD8a molecule
CELF2 CUGBP, Elav-like family member 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DLK1 delta-like 1 homolog (Drosophila)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
IGHM immunoglobulin heavy constant mu
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
KRT7 keratin 7, type II
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MDK midkine (neurite growth-promoting factor 2)
MKNK1 MAP kinase interacting serine/threonine kinase 1
NCF2 neutrophil cytosolic factor 2
NMU neuromedin U
PAX6 paired box 6
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RNF167 ring finger protein 167
RTN1 reticulon 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB2A2 secretoglobin, family 2A, member 2
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
AGTR1 angiotensin II receptor, type 1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLIC4 chloride intracellular channel 4
CRELD2 cysteine-rich with EGF-like domains 2
CXCL12 chemokine (C-X-C motif) ligand 12
DIO1 deiodinase, iodothyronine, type I
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM46A family with sequence similarity 46, member A
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GADD45B growth arrest and DNA-damage-inducible, beta
GMDS GDP-mannose 4,6-dehydratase
KLF4 Kruppel-like factor 4 (gut)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPY1R neuropeptide Y receptor Y1
NREP neuronal regeneration related protein
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8