BRD-A08709697_Heliotrine_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

96 genes differentially expressed following the BRD-A08709697_Heliotrine_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
APOA1 apolipoprotein A-I
C9ORF3 chromosome 9 open reading frame 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSTA cystatin A (stefin A)
CX3CL1 chemokine (C-X3-C motif) ligand 1
EMX2 empty spiracles homeobox 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
ESM1 endothelial cell-specific molecule 1
FABP6 fatty acid binding protein 6, ileal
FGFR3 fibroblast growth factor receptor 3
FZD5 frizzled class receptor 5
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRB7 growth factor receptor-bound protein 7
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
MT1M metallothionein 1M
MUC4 mucin 4, cell surface associated
MYOF myoferlin
NLRP2 NLR family, pyrin domain containing 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLFM4 olfactomedin 4
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PON3 paraoxonase 3
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
PTPRO protein tyrosine phosphatase, receptor type, O
RASL12 RAS-like, family 12
RGCC regulator of cell cycle
RNASE4 ribonuclease, RNase A family, 4
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SOX17 SRY (sex determining region Y)-box 17
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
AMIGO2 adhesion molecule with Ig-like domain 2
ASPN asporin
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BASP1 brain abundant, membrane attached signal protein 1
C6ORF48 chromosome 6 open reading frame 48
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL10A1 collagen, type X, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CTSK cathepsin K
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DACT1 dishevelled-binding antagonist of beta-catenin 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DCN decorin
DHCR7 7-dehydrocholesterol reductase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
F13A1 coagulation factor XIII, A1 polypeptide
GAS1 growth arrest-specific 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GOLM1 golgi membrane protein 1
GSTM3 glutathione S-transferase mu 3 (brain)
HOMER1 homer scaffolding protein 1
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
IRF7 interferon regulatory factor 7
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MYO6 myosin VI
NPY1R neuropeptide Y receptor Y1
PI3 peptidase inhibitor 3, skin-derived
RAD51C RAD51 paralog C
REEP5 receptor accessory protein 5
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIM2 single-minded family bHLH transcription factor 2
SOX4 SRY (sex determining region Y)-box 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM45A transmembrane protein 45A
TXNDC9 thioredoxin domain containing 9