BRD-A08662020_MLS-0391005_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-A08662020_MLS-0391005_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AZU1 azurocidin 1
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
CCL2 chemokine (C-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GPRC5B G protein-coupled receptor, class C, group 5, member B
ICAM1 intercellular adhesion molecule 1
IL32 interleukin 32
LRRC17 leucine rich repeat containing 17
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PEG10 paternally expressed 10
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PODXL podocalyxin-like
PTX3 pentraxin 3, long
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SDC4 syndecan 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
TACSTD2 tumor-associated calcium signal transducer 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDIT4 DNA-damage-inducible transcript 4
FHL1 four and a half LIM domains 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI16 interferon, gamma-inducible protein 16
IFI6 interferon, alpha-inducible protein 6
IL13RA2 interleukin 13 receptor, alpha 2
MMP9 matrix metallopeptidase 9
PDE4DIP phosphodiesterase 4D interacting protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
REEP1 receptor accessory protein 1
SYNM synemin, intermediate filament protein
TGM2 transglutaminase 2
WNT5A wingless-type MMTV integration site family, member 5A