BRD-A08610364_NCGC00181375-01_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A08610364_NCGC00181375-01_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABAT 4-aminobutyrate aminotransferase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
CARS cysteinyl-tRNA synthetase
CD24 CD24 molecule
CLIC4 chloride intracellular channel 4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPRS glutamyl-prolyl-tRNA synthetase
FAM129A family with sequence similarity 129, member A
GARS glycyl-tRNA synthetase
GATA6 GATA binding protein 6
GRB10 growth factor receptor-bound protein 10
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
LDLR low density lipoprotein receptor
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MSMO1 methylsterol monooxygenase 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
POU2AF1 POU class 2 associating factor 1
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFRP1 secreted frizzled-related protein 1
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SORD sorbitol dehydrogenase
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TFF1 trefoil factor 1
TSC22D3 TSC22 domain family, member 3
XBP1 X-box binding protein 1
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase

decreased expression

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
ATP9A ATPase, class II, type 9A
CADM1 cell adhesion molecule 1
CDK6 cyclin-dependent kinase 6
CLEC2B C-type lectin domain family 2, member B
EFNA1 ephrin-A1
EIF5A eukaryotic translation initiation factor 5A
GRB7 growth factor receptor-bound protein 7
PLK1 polo-like kinase 1
PMP22 peripheral myelin protein 22
ST18 suppression of tumorigenicity 18, zinc finger