BRD-A08003242_RHODOMYRTOXIN B_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A08003242_RHODOMYRTOXIN B_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADGRG2 adhesion G protein-coupled receptor G2
ADGRG6 adhesion G protein-coupled receptor G6
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AXIN1 axin 1
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
BHLHE40 basic helix-loop-helix family, member e40
CCNG2 cyclin G2
CHRDL1 chordin-like 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
ENAH enabled homolog (Drosophila)
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FASN fatty acid synthase
FLNA filamin A, alpha
FOXO3 forkhead box O3
G6PD glucose-6-phosphate dehydrogenase
INSIG1 insulin induced gene 1
JUND jun D proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KDM4B lysine (K)-specific demethylase 4B
LDLR low density lipoprotein receptor
LPP LIM domain containing preferred translocation partner in lipoma
MT1X metallothionein 1X
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NFIL3 nuclear factor, interleukin 3 regulated
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PROM1 prominin 1
PRR7 proline rich 7 (synaptic)
RHOB ras homolog family member B
RND3 Rho family GTPase 3
RRAGD Ras-related GTP binding D
S100A14 S100 calcium binding protein A14
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
STC2 stanniocalcin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUBB2B tubulin, beta 2B class IIb
UGDH UDP-glucose 6-dehydrogenase
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ATF5 activating transcription factor 5
C8ORF33 chromosome 8 open reading frame 33
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCNE2 cyclin E2
CDC25A cell division cycle 25A
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EFNB2 ephrin-B2
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HSPA1A heat shock 70kDa protein 1A
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MNDA myeloid cell nuclear differentiation antigen
NID2 nidogen 2 (osteonidogen)
SESN1 sestrin 1
SFPQ splicing factor proline/glutamine-rich
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)