BRD-A08003242_RHODOMYRTOXIN B_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-A08003242_RHODOMYRTOXIN B_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDK4 cyclin-dependent kinase 4
CHRDL1 chordin-like 1
CLTB clathrin, light chain B
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHCR7 7-dehydrocholesterol reductase
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FADS1 fatty acid desaturase 1
FXYD5 FXYD domain containing ion transport regulator 5
GANAB glucosidase, alpha; neutral AB
GAS7 growth arrest-specific 7
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGF2R insulin-like growth factor 2 receptor
INSIG1 insulin induced gene 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LAMB1 laminin, beta 1
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MSMO1 methylsterol monooxygenase 1
NELL2 NEL-like 2 (chicken)
NLGN4X neuroligin 4, X-linked
RAP1GAP RAP1 GTPase activating protein
REEP1 receptor accessory protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQLE squalene epoxidase
SRSF11 serine/arginine-rich splicing factor 11
SST somatostatin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
C6ORF62 chromosome 6 open reading frame 62
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CSTA cystatin A (stefin A)
DCN decorin
EHF ets homologous factor
ELF5 E74-like factor 5 (ets domain transcription factor)
ENOSF1 enolase superfamily member 1
EPN2 epsin 2
FMO2 flavin containing monooxygenase 2 (non-functional)
FXYD3 FXYD domain containing ion transport regulator 3
GJA1 gap junction protein, alpha 1, 43kDa
HOPX HOP homeobox
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LAMP3 lysosomal-associated membrane protein 3
LTF lactotransferrin
LXN latexin
MAP7 microtubule-associated protein 7
NEBL nebulette
ODC1 ornithine decarboxylase 1
RAB27A RAB27A, member RAS oncogene family
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOX9 SRY (sex determining region Y)-box 9
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
SRGN serglycin
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TRIM13 tripartite motif containing 13