BRD-A08003242_RHODOMYRTOXIN B_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

163 genes differentially expressed following the BRD-A08003242_RHODOMYRTOXIN B_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AGA aspartylglucosaminidase
AKAP12 A kinase (PRKA) anchor protein 12
ANXA1 annexin A1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX3 armadillo repeat containing, X-linked 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BIRC3 baculoviral IAP repeat containing 3
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CARS cysteinyl-tRNA synthetase
CCL20 chemokine (C-C motif) ligand 20
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CIB1 calcium and integrin binding 1 (calmyrin)
COL6A2 collagen, type VI, alpha 2
CREM cAMP responsive element modulator
CTH cystathionine gamma-lyase
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPRS glutamyl-prolyl-tRNA synthetase
FADS1 fatty acid desaturase 1
FBXO11 F-box protein 11
FHL2 four and a half LIM domains 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GAGE3 G antigen 3
GARS glycyl-tRNA synthetase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GOLGA4 golgin A4
GRB10 growth factor receptor-bound protein 10
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
IGLV2-23 immunoglobulin lambda variable 2-23
IL6 interleukin 6
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
KRT18 keratin 18, type I
LCN2 lipocalin 2
LIF leukemia inhibitory factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
MARS methionyl-tRNA synthetase
MLPH melanophilin
MOCOS molybdenum cofactor sulfurase
MT1X metallothionein 1X
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RHOB ras homolog family member B
RNMT RNA (guanine-7-) methyltransferase
SARS seryl-tRNA synthetase
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC24D SEC24 family member D
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SSX1 synovial sarcoma, X breakpoint 1
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF3 trefoil factor 3 (intestinal)
TGIF1 TGFB-induced factor homeobox 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A
WDR45 WD repeat domain 45
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)
XPOT exportin, tRNA

decreased expression

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKR1C1 aldo-keto reductase family 1, member C1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CA2 carbonic anhydrase II
CANT1 calcium activated nucleotidase 1
CCL4 chemokine (C-C motif) ligand 4
CD24 CD24 molecule
CDC42 cell division cycle 42
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CERK ceramide kinase
CSRP2 cysteine and glycine-rich protein 2
CTSZ cathepsin Z
CXCL14 chemokine (C-X-C motif) ligand 14
DPP4 dipeptidyl-peptidase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPHA3 EPH receptor A3
FBXL12 F-box and leucine-rich repeat protein 12
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
FZD5 frizzled class receptor 5
GJA1 gap junction protein, alpha 1, 43kDa
HAT1 histone acetyltransferase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICMT isoprenylcysteine carboxyl methyltransferase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IGHMBP2 immunoglobulin mu binding protein 2
KANK1 KN motif and ankyrin repeat domains 1
KRT16 keratin 16, type I
LRRN3 leucine rich repeat neuronal 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP7 microtubule-associated protein 7
MDFIC MyoD family inhibitor domain containing
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PER3 period circadian clock 3
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLBD1 phospholipase B domain containing 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
S100A9 S100 calcium binding protein A9
SAC3D1 SAC3 domain containing 1
SDC2 syndecan 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOX9 SRY (sex determining region Y)-box 9
STOM stomatin
TCF4 transcription factor 4
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TUBA4A tubulin, alpha 4a
UBE2N ubiquitin-conjugating enzyme E2N
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNG uracil-DNA glycosylase
ZNF512B zinc finger protein 512B