BRD-A07893380_Vigabatrin_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-A07893380_Vigabatrin_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALR calreticulin
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK19 cyclin-dependent kinase 19
CEMIP cell migration inducing protein, hyaluronan binding
CHN1 chimerin 1
CLEC11A C-type lectin domain family 11, member A
COL11A1 collagen, type XI, alpha 1
COL13A1 collagen, type XIII, alpha 1
CPE carboxypeptidase E
CSK c-src tyrosine kinase
CSTA cystatin A (stefin A)
FGF13 fibroblast growth factor 13
FILIP1L filamin A interacting protein 1-like
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GOLGA8A golgin A8 family, member A
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPA4 heat shock 70kDa protein 4
IER5 immediate early response 5
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MSLN mesothelin
MSMB microseminoprotein, beta-
MYO5A myosin VA (heavy chain 12, myoxin)
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDZRN3 PDZ domain containing ring finger 3
PRAME preferentially expressed antigen in melanoma
PRUNE2 prune homolog 2 (Drosophila)
PTPRO protein tyrosine phosphatase, receptor type, O
RAB27A RAB27A, member RAS oncogene family
RAD51C RAD51 paralog C
RGS10 regulator of G-protein signaling 10
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RTN1 reticulon 1
SFRP1 secreted frizzled-related protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHOX2 short stature homeobox 2
SMC1A structural maintenance of chromosomes 1A
SPON2 spondin 2, extracellular matrix protein
TGFA transforming growth factor, alpha
TM9SF3 transmembrane 9 superfamily member 3
VEGFA vascular endothelial growth factor A
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP4A charged multivesicular body protein 4A
CLU clusterin
CRIP1 cysteine-rich protein 1 (intestinal)
CYB5A cytochrome b5 type A (microsomal)
DAPK1 death-associated protein kinase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM63A family with sequence similarity 63, member A
GJA1 gap junction protein, alpha 1, 43kDa
GSTM3 glutathione S-transferase mu 3 (brain)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
LAMP1 lysosomal-associated membrane protein 1
LYPLA1 lysophospholipase I
MCL1 myeloid cell leukemia 1
PLA2G16 phospholipase A2, group XVI
PPA1 pyrophosphatase (inorganic) 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RBP1 retinol binding protein 1, cellular
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TFF3 trefoil factor 3 (intestinal)
TJP2 tight junction protein 2
TRAPPC3 trafficking protein particle complex 3
U2AF1 U2 small nuclear RNA auxiliary factor 1
VAMP3 vesicle-associated membrane protein 3