BRD-A07875874_Cilnidipine_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-A07875874_Cilnidipine_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRL2 adhesion G protein-coupled receptor L2
ANPEP alanyl (membrane) aminopeptidase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CADM1 cell adhesion molecule 1
CCNB2 cyclin B2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC2B C-type lectin domain family 2, member B
CPD carboxypeptidase D
DACH1 dachshund family transcription factor 1
DEPTOR DEP domain containing MTOR-interacting protein
DPYSL3 dihydropyrimidinase-like 3
EGR1 early growth response 1
FBP1 fructose-1,6-bisphosphatase 1
FBXO21 F-box protein 21
FGFR3 fibroblast growth factor receptor 3
FXYD6 FXYD domain containing ion transport regulator 6
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IFI44 interferon-induced protein 44
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IGLJ3 immunoglobulin lambda joining 3
INA internexin neuronal intermediate filament protein, alpha
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LAMP5 lysosomal-associated membrane protein family, member 5
LMO3 LIM domain only 3 (rhombotin-like 2)
MEIS2 Meis homeobox 2
MMP2 matrix metallopeptidase 2
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NCAM1 neural cell adhesion molecule 1
NEB nebulin
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR2F6 nuclear receptor subfamily 2, group F, member 6
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPAP2A phosphatidic acid phosphatase type 2A
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SCGB1D2 secretoglobin, family 1D, member 2
SFRP1 secreted frizzled-related protein 1
SORBS2 sorbin and SH3 domain containing 2
ST18 suppression of tumorigenicity 18, zinc finger
STC1 stanniocalcin 1
TCF21 transcription factor 21
TEK TEK tyrosine kinase, endothelial
TMSB15A thymosin beta 15a
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACOT9 acyl-CoA thioesterase 9
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
ARMCX6 armadillo repeat containing, X-linked 6
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTSH cathepsin H
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ECM1 extracellular matrix protein 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ETFB electron-transfer-flavoprotein, beta polypeptide
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
FSCN1 fascin actin-bundling protein 1
GAS1 growth arrest-specific 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HPRT1 hypoxanthine phosphoribosyltransferase 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0485 uncharacterized LOC57235
KIF14 kinesin family member 14
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LOXL1 lysyl oxidase-like 1
LPAR1 lysophosphatidic acid receptor 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MSN moesin
NUP62 nucleoporin 62kDa
PKM pyruvate kinase, muscle
PPA1 pyrophosphatase (inorganic) 1
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRMT1 protein arginine methyltransferase 1
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SLC35F2 solute carrier family 35, member F2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLIRP SRA stem-loop interacting RNA binding protein
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSPAN3 tetraspanin 3
UGCG UDP-glucose ceramide glucosyltransferase