BRD-A07875874_Cilnidipine_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-A07875874_Cilnidipine_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CCDC85B coiled-coil domain containing 85B
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN3 claudin 3
COMP cartilage oligomeric matrix protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
ECM1 extracellular matrix protein 1
EGFR epidermal growth factor receptor
FBP1 fructose-1,6-bisphosphatase 1
G6PD glucose-6-phosphate dehydrogenase
GLRX glutaredoxin (thioltransferase)
INHBA inhibin, beta A
LAMA3 laminin, alpha 3
LOX lysyl oxidase
MSMO1 methylsterol monooxygenase 1
MVP major vault protein
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
PLAU plasminogen activator, urokinase
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPAG4 sperm associated antigen 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STX1A syntaxin 1A (brain)
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF1 activating transcription factor 1
BACE2 beta-site APP-cleaving enzyme 2
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5 eukaryotic translation initiation factor 5
FCGBP Fc fragment of IgG binding protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLK2 polo-like kinase 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TFAM transcription factor A, mitochondrial