BRD-A07875874_Cilnidipine_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-A07875874_Cilnidipine_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX4 brain expressed, X-linked 4
C1QB complement component 1, q subcomponent, B chain
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CD14 CD14 molecule
CHGB chromogranin B
CLC Charcot-Leyden crystal galectin
CLIC4 chloride intracellular channel 4
CSTA cystatin A (stefin A)
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2A integral membrane protein 2A
LCN2 lipocalin 2
MAP7 microtubule-associated protein 7
MCOLN1 mucolipin 1
MFAP5 microfibrillar associated protein 5
MMP9 matrix metallopeptidase 9
PCSK1 proprotein convertase subtilisin/kexin type 1
PERP PERP, TP53 apoptosis effector
PLAU plasminogen activator, urokinase
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCT glutaminyl-peptide cyclotransferase
RRAGD Ras-related GTP binding D
S100A8 S100 calcium binding protein A8
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
TDO2 tryptophan 2,3-dioxygenase
TMEM176B transmembrane protein 176B
TPD52 tumor protein D52
WARS tryptophanyl-tRNA synthetase
WT1 Wilms tumor 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOLD1 apolipoprotein L domain containing 1
B3GNT1
CA12 carbonic anhydrase XII
CSRP2 cysteine and glycine-rich protein 2
CTSH cathepsin H
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB2 erb-b2 receptor tyrosine kinase 2
FLRT3 fibronectin leucine rich transmembrane protein 3
GSTM3 glutathione S-transferase mu 3 (brain)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MSMO1 methylsterol monooxygenase 1
MYBPC1 myosin binding protein C, slow type
MYH10 myosin, heavy chain 10, non-muscle
NQO1 NAD(P)H dehydrogenase, quinone 1
PDZK1 PDZ domain containing 1
PYCARD PYD and CARD domain containing
RPL37A ribosomal protein L37a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TLR4 toll-like receptor 4