BRD-A07780951_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A07780951_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AMD1 adenosylmethionine decarboxylase 1
ASPN asporin
ATR ATR serine/threonine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DKC1 dyskeratosis congenita 1, dyskerin
DPH2 DPH2 homolog (S. cerevisiae)
DUSP14 dual specificity phosphatase 14
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ENDOD1 endonuclease domain containing 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GLS glutaminase
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GRWD1 glutamate-rich WD repeat containing 1
GSPT1 G1 to S phase transition 1
GTPBP4 GTP binding protein 4
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
INPP1 inositol polyphosphate-1-phosphatase
ITGA6 integrin, alpha 6
IVNS1ABP influenza virus NS1A binding protein
KLF4 Kruppel-like factor 4 (gut)
LPL lipoprotein lipase
MALT1 MALT1 paracaspase
MAP2K3 mitogen-activated protein kinase kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCAM melanoma cell adhesion molecule
NAMPT nicotinamide phosphoribosyltransferase
NEBL nebulette
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NUP98 nucleoporin 98kDa
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PMP22 peripheral myelin protein 22
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNP purine nucleoside phosphorylase
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
RPP40 ribonuclease P/MRP 40kDa subunit
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRP1B ribosomal RNA processing 1B
SCGB2A2 secretoglobin, family 2A, member 2
SIK1 salt-inducible kinase 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SPARCL1 SPARC-like 1 (hevin)
SRPRB signal recognition particle receptor, B subunit
TMEM2 transmembrane protein 2
TPM4 tropomyosin 4

decreased expression

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
CD52 CD52 molecule
CNIH4 cornichon family AMPA receptor auxiliary protein 4
DPYSL3 dihydropyrimidinase-like 3
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HELLS helicase, lymphoid-specific
INSIG1 insulin induced gene 1
KIF14 kinesin family member 14
MSLN mesothelin
NDC80 NDC80 kinetochore complex component
RAB13 RAB13, member RAS oncogene family
SC5D sterol-C5-desaturase
SQLE squalene epoxidase
TTK TTK protein kinase