BRD-A07614565_7969312_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-A07614565_7969312_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOA aldolase A, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ATF5 activating transcription factor 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1S complement component 1, s subcomponent
CBR1 carbonyl reductase 1
CCND1 cyclin D1
CD24 CD24 molecule
CHPT1 choline phosphotransferase 1
COL6A1 collagen, type VI, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
ERO1L ERO1-like (S. cerevisiae)
FAM162A family with sequence similarity 162, member A
GAL galanin/GMAP prepropeptide
GLA galactosidase, alpha
GPI glucose-6-phosphate isomerase
GSN gelsolin
H1F0 H1 histone family, member 0
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ISG15 ISG15 ubiquitin-like modifier
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPT microtubule-associated protein tau
MKNK2 MAP kinase interacting serine/threonine kinase 2
MSX1 msh homeobox 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRN1 neuritin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKP phosphofructokinase, platelet
PIP prolactin-induced protein
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLPI secretory leukocyte peptidase inhibitor
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
TWF2 twinfilin actin binding protein 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP29 Rho GTPase activating protein 29
ARMCX2 armadillo repeat containing, X-linked 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG2 BTG family, member 2
CAV2 caveolin 2
CCND2 cyclin D2
CDC20 cell division cycle 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CNN3 calponin 3, acidic
COL5A2 collagen, type V, alpha 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DLC1 DLC1 Rho GTPase activating protein
DOCK9 dedicator of cytokinesis 9
EBNA1BP2 EBNA1 binding protein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR6 lysophosphatidic acid receptor 6
LRRN3 leucine rich repeat neuronal 3
LXN latexin
MDFIC MyoD family inhibitor domain containing
MYH10 myosin, heavy chain 10, non-muscle
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
POSTN periostin, osteoblast specific factor
PTN pleiotrophin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
STON1 stonin 1
SULF1 sulfatase 1
TMEM97 transmembrane protein 97
TSPAN12 tetraspanin 12
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon