BRD-A07614565_7969312_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A07614565_7969312_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
AKAP12 A kinase (PRKA) anchor protein 12
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CELF2 CUGBP, Elav-like family member 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTH cystathionine gamma-lyase
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DUSP3 dual specificity phosphatase 3
EIF5 eukaryotic translation initiation factor 5
ENO2 enolase 2 (gamma, neuronal)
GDF15 growth differentiation factor 15
GSTM3 glutathione S-transferase mu 3 (brain)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IDS iduronate 2-sulfatase
KDM3A lysine (K)-specific demethylase 3A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PEG3 paternally expressed 3
PGK1 phosphoglycerate kinase 1
PHGDH phosphoglycerate dehydrogenase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PSAP prosaposin
RALGDS ral guanine nucleotide dissociation stimulator
RGS1 regulator of G-protein signaling 1
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
RTN4 reticulon 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
SQSTM1 sequestosome 1
TOX3 TOX high mobility group box family member 3
TSC22D3 TSC22 domain family, member 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CALB1 calbindin 1, 28kDa
CCNA2 cyclin A2
CD59 CD59 molecule, complement regulatory protein
EREG epiregulin
GRIA2 glutamate receptor, ionotropic, AMPA 2
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INHBA inhibin, beta A
LEF1 lymphoid enhancer-binding factor 1
NOV nephroblastoma overexpressed
POSTN periostin, osteoblast specific factor
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
ZNF586 zinc finger protein 586
ZW10 zw10 kinetochore protein