BRD-A07000685_HYDROCORTISONE HEMISUCCINATE_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

117 genes differentially expressed following the BRD-A07000685_HYDROCORTISONE HEMISUCCINATE_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACSL1 acyl-CoA synthetase long-chain family member 1
C10ORF10 chromosome 10 open reading frame 10
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPM carboxypeptidase M
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
FKBP5 FK506 binding protein 5
FLG filaggrin
FTH1 ferritin, heavy polypeptide 1
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GPM6B glycoprotein M6B
HLA-E major histocompatibility complex, class I, E
HOXA5 homeobox A5
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
LPIN1 lipin 1
MCL1 myeloid cell leukemia 1
MTSS1 metastasis suppressor 1
MYO1B myosin IB
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NELL2 NEL-like 2 (chicken)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OPN3 opsin 3
PDLIM1 PDZ and LIM domain 1
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PXN paxillin
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RORA RAR-related orphan receptor A
S100A7 S100 calcium binding protein A7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIK1 salt-inducible kinase 1
SOD2 superoxide dismutase 2, mitochondrial
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYBU syntabulin (syntaxin-interacting)
TCTA T-cell leukemia translocation altered
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP8 vesicle-associated membrane protein 8
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
AXL AXL receptor tyrosine kinase
BMP2 bone morphogenetic protein 2
CCL2 chemokine (C-C motif) ligand 2
CD9 CD9 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLU clusterin
COLEC12 collectin sub-family member 12
CYBRD1 cytochrome b reductase 1
FAM129A family with sequence similarity 129, member A
FGFR3 fibroblast growth factor receptor 3
FOSL1 FOS-like antigen 1
FOXF1 forkhead box F1
FOXG1 forkhead box G1
GREM1 gremlin 1, DAN family BMP antagonist
H1F0 H1 histone family, member 0
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0226L KIAA0226-like
KRT4 keratin 4, type II
LIF leukemia inhibitory factor
LMO4 LIM domain only 4
MAP7 microtubule-associated protein 7
MDK midkine (neurite growth-promoting factor 2)
NUP85 nucleoporin 85kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCP4 Purkinje cell protein 4
PMP22 peripheral myelin protein 22
PNMA2 paraneoplastic Ma antigen 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QKI QKI, KH domain containing, RNA binding
RAB31 RAB31, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF43 ring finger protein 43
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPARCL1 SPARC-like 1 (hevin)
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)