BRD-A06929388_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A06929388_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
BEX4 brain expressed, X-linked 4
CCNG2 cyclin G2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
COBL cordon-bleu WH2 repeat protein
COL2A1 collagen, type II, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DENND1B DENN/MADD domain containing 1B
DLK1 delta-like 1 homolog (Drosophila)
FAM69A family with sequence similarity 69, member A
FGFR1 fibroblast growth factor receptor 1
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFI6 interferon, alpha-inducible protein 6
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
MAP7 microtubule-associated protein 7
MGMT O-6-methylguanine-DNA methyltransferase
MMP11 matrix metallopeptidase 11
MYC v-myc avian myelocytomatosis viral oncogene homolog
NUPR1 nuclear protein, transcriptional regulator, 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAX5 paired box 5
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
RGCC regulator of cell cycle
RGS10 regulator of G-protein signaling 10
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERTAD2 SERTA domain containing 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TXNRD1 thioredoxin reductase 1
VGLL4 vestigial-like family member 4
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASCL1 achaete-scute family bHLH transcription factor 1
BCLAF1 BCL2-associated transcription factor 1
CAST calpastatin
CCNA2 cyclin A2
CD320 CD320 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CTSH cathepsin H
CXADR coxsackie virus and adenovirus receptor
CXCL9 chemokine (C-X-C motif) ligand 9
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPYSL3 dihydropyrimidinase-like 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
GPX2 glutathione peroxidase 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LIPG lipase, endothelial
MARCKSL1 MARCKS-like 1
MLEC malectin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR2F2 nuclear receptor subfamily 2, group F, member 2
S100A10 S100 calcium binding protein A10
SCNN1A sodium channel, non voltage gated 1 alpha subunit
TAGLN2 transgelin 2
TGM2 transglutaminase 2