BRD-A06929388_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-A06929388_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BRD2 bromodomain containing 2
BTN3A2 butyrophilin, subfamily 3, member A2
CD163 CD163 molecule
CLCN3 chloride channel, voltage-sensitive 3
CTH cystathionine gamma-lyase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
EGFR epidermal growth factor receptor
FAM129A family with sequence similarity 129, member A
FLOT1 flotillin 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
KLF4 Kruppel-like factor 4 (gut)
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LOX lysyl oxidase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NFIL3 nuclear factor, interleukin 3 regulated
NQO2 NAD(P)H dehydrogenase, quinone 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRCAM neuronal cell adhesion molecule
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PERP PERP, TP53 apoptosis effector
PGD phosphogluconate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PKP1 plakophilin 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RAD23B RAD23 homolog B (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
STC2 stanniocalcin 2
TRIB3 tribbles pseudokinase 3
TXNL4B thioredoxin-like 4B
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRF5 adhesion G protein-coupled receptor F5
ALB albumin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C7 complement component 7
CNN1 calponin 1, basic, smooth muscle
CTSH cathepsin H
FBP1 fructose-1,6-bisphosphatase 1
GOLGA8A golgin A8 family, member A
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MATN2 matrilin 2
MGP matrix Gla protein
NAV2 neuron navigator 2
NFIB nuclear factor I/B
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGN osteoglycin
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDZRN3 PDZ domain containing ring finger 3
PLAGL1 pleiomorphic adenoma gene-like 1
PLS3 plastin 3
PNN pinin, desmosome associated protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB4A RAB4A, member RAS oncogene family
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPS11 ribosomal protein S11
SELENBP1 selenium binding protein 1
SFRP1 secreted frizzled-related protein 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TARP TCR gamma alternate reading frame protein
TESC tescalcin
TFRC transferrin receptor
VIM vimentin