BRD-A06929388_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A06929388_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
ATP11B ATPase, class VI, type 11B
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CBR3 carbonyl reductase 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GAB2 GRB2-associated binding protein 2
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLF4 Kruppel-like factor 4 (gut)
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NDRG1 N-myc downstream regulated 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIR pirin (iron-binding nuclear protein)
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RGCC regulator of cell cycle
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TRIM2 tripartite motif containing 2
UGDH UDP-glucose 6-dehydrogenase
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPX3 glutathione peroxidase 3
HOPX HOP homeobox
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
LMO2 LIM domain only 2 (rhombotin-like 1)
MXRA7 matrix-remodelling associated 7
NMU neuromedin U
OXTR oxytocin receptor
PLAT plasminogen activator, tissue
PODXL podocalyxin-like
PRDX2 peroxiredoxin 2
PSPH phosphoserine phosphatase
PVALB parvalbumin
RPS26 ribosomal protein S26
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
TNS1 tensin 1
TNS3 tensin 3