BRD-A06929388_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

142 genes differentially expressed following the BRD-A06929388_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BCL6 B-cell CLL/lymphoma 6
BMP2 bone morphogenetic protein 2
BTG1 B-cell translocation gene 1, anti-proliferative
CBS cystathionine-beta-synthase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CSRP1 cysteine and glycine-rich protein 1
CYBA cytochrome b-245, alpha polypeptide
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPP4 dipeptidyl-peptidase 4
DUSP6 dual specificity phosphatase 6
EDN3 endothelin 3
EFNA1 ephrin-A1
EIF5 eukaryotic translation initiation factor 5
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR2 fibroblast growth factor receptor 2
FOXG1 forkhead box G1
FST follistatin
FXYD3 FXYD domain containing ion transport regulator 3
GABPB1 GA binding protein transcription factor, beta subunit 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IER5 immediate early response 5
IFNGR1 interferon gamma receptor 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
JCHAIN joining chain of multimeric IgA and IgM
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLF4 Kruppel-like factor 4 (gut)
LAMA4 laminin, alpha 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCL1 myeloid cell leukemia 1
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MYO10 myosin X
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFA platelet-derived growth factor alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PROM1 prominin 1
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RTN2 reticulon 2
SERTAD2 SERTA domain containing 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGIF1 TGFB-induced factor homeobox 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TPST2 tyrosylprotein sulfotransferase 2
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TXNL4B thioredoxin-like 4B
WNT5B wingless-type MMTV integration site family, member 5B
XBP1 X-box binding protein 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACOT9 acyl-CoA thioesterase 9
ACTA2 actin, alpha 2, smooth muscle, aorta
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CALD1 caldesmon 1
CBR3 carbonyl reductase 3
CCNF cyclin F
CD24 CD24 molecule
CDC42 cell division cycle 42
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHPT1 choline phosphotransferase 1
CXADR coxsackie virus and adenovirus receptor
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
DIO2 deiodinase, iodothyronine, type II
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GOLGA8A golgin A8 family, member A
GSTM3 glutathione S-transferase mu 3 (brain)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSDL2 hydroxysteroid dehydrogenase like 2
IGF1 insulin-like growth factor 1 (somatomedin C)
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LRRN3 leucine rich repeat neuronal 3
MATN2 matrilin 2
MRPS12 mitochondrial ribosomal protein S12
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR2F1 nuclear receptor subfamily 2, group F, member 1
PALLD palladin, cytoskeletal associated protein
PBX1 pre-B-cell leukemia homeobox 1
PGAM1 phosphoglycerate mutase 1 (brain)
PLK1 polo-like kinase 1
RNF167 ring finger protein 167
RPL39L ribosomal protein L39-like
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP4 secreted frizzled-related protein 4
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SORD sorbitol dehydrogenase
STX1A syntaxin 1A (brain)
THBS1 thrombospondin 1
TMEM14A transmembrane protein 14A
TXNDC9 thioredoxin domain containing 9
TXNL4A thioredoxin-like 4A