BRD-A06909528_MLS-0315871.0001_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-A06909528_MLS-0315871.0001_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
AZU1 azurocidin 1
BHLHE41 basic helix-loop-helix family, member e41
CAPN2 calpain 2, (m/II) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB2 cyclin B2
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD9 CD9 molecule
CHIT1 chitinase 1 (chitotriosidase)
CLDN8 claudin 8
CLEC11A C-type lectin domain family 11, member A
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CTSK cathepsin K
DENND1B DENN/MADD domain containing 1B
EFNA5 ephrin-A5
ELANE elastase, neutrophil expressed
ESRP1 epithelial splicing regulatory protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVI2A ecotropic viral integration site 2A
FAM69A family with sequence similarity 69, member A
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA3 GATA binding protein 3
GPNMB glycoprotein (transmembrane) nmb
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB7 growth factor receptor-bound protein 7
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KYNU kynureninase
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MT1HL1 metallothionein 1H-like 1
NARFL nuclear prelamin A recognition factor-like
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
PDE4B phosphodiesterase 4B, cAMP-specific
POSTN periostin, osteoblast specific factor
PTK2B protein tyrosine kinase 2 beta
PTPRO protein tyrosine phosphatase, receptor type, O
PXN paxillin
PYCARD PYD and CARD domain containing
RAB25 RAB25, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SQRDL sulfide quinone reductase-like (yeast)
SRGN serglycin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TACSTD2 tumor-associated calcium signal transducer 2
THBS2 thrombospondin 2
TRIB3 tribbles pseudokinase 3
UMOD uromodulin
VEGFA vascular endothelial growth factor A
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ANO1 anoctamin 1, calcium activated chloride channel
BST2 bone marrow stromal cell antigen 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLU clusterin
COCH cochlin
COL4A2 collagen, type IV, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL14 chemokine (C-X-C motif) ligand 14
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FSTL1 follistatin-like 1
HBB hemoglobin, beta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IFITM2 interferon induced transmembrane protein 2
KRT10 keratin 10, type I
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIG1 ligase I, DNA, ATP-dependent
LRRN3 leucine rich repeat neuronal 3
MARCKSL1 MARCKS-like 1
MATN2 matrilin 2
MMD monocyte to macrophage differentiation-associated
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
NTS neurotensin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAGL1 pleiomorphic adenoma gene-like 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRDX2 peroxiredoxin 2
RBBP4 retinoblastoma binding protein 4
RBP1 retinol binding protein 1, cellular
RPL36 ribosomal protein L36
SACS sacsin molecular chaperone
SCRN1 secernin 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TSPAN13 tetraspanin 13
TUBB tubulin, beta class I