BRD-A06909528_MLS-0315871.0001_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

98 genes differentially expressed following the BRD-A06909528_MLS-0315871.0001_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ADRB2 adrenoceptor beta 2, surface
ASXL2 additional sex combs like transcriptional regulator 2
C6ORF62 chromosome 6 open reading frame 62
C8ORF4 chromosome 8 open reading frame 4
CD9 CD9 molecule
COL6A3 collagen, type VI, alpha 3
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
GATA3 GATA binding protein 3
HOXC6 homeobox C6
HP haptoglobin
IDE insulin-degrading enzyme
IGFBP4 insulin-like growth factor binding protein 4
IL1R2 interleukin 1 receptor, type II
IL7R interleukin 7 receptor
JADE2 jade family PHD finger 2
KRT15 keratin 15, type I
LEF1 lymphoid enhancer-binding factor 1
LPL lipoprotein lipase
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGC progastricsin (pepsinogen C)
PIR pirin (iron-binding nuclear protein)
PTGES prostaglandin E synthase
RAB31 RAB31, member RAS oncogene family
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERINC5 serine incorporator 5
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
SSBP2 single-stranded DNA binding protein 2
SYT1 synaptotagmin I
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TIAM1 T-cell lymphoma invasion and metastasis 1
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
WNT5A wingless-type MMTV integration site family, member 5A
WWP1 WW domain containing E3 ubiquitin protein ligase 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AHCY adenosylhomocysteinase
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ARG2 arginase 2
ASPH aspartate beta-hydroxylase
ASS1 argininosuccinate synthase 1
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
C1ORF106 chromosome 1 open reading frame 106
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPZB capping protein (actin filament) muscle Z-line, beta
CAST calpastatin
CCNI cyclin I
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CNIH1 cornichon family AMPA receptor auxiliary protein 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
EIF5A eukaryotic translation initiation factor 5A
ERGIC3 ERGIC and golgi 3
FGG fibrinogen gamma chain
FXYD6 FXYD domain containing ion transport regulator 6
GNAS GNAS complex locus
GPI glucose-6-phosphate isomerase
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
LAMB1 laminin, beta 1
LGALS1 lectin, galactoside-binding, soluble, 1
LONP1 lon peptidase 1, mitochondrial
MAP7 microtubule-associated protein 7
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NFIB nuclear factor I/B
NPTX2 neuronal pentraxin II
NXN nucleoredoxin
PAM peptidylglycine alpha-amidating monooxygenase
PEG10 paternally expressed 10
PGAM1 phosphoglycerate mutase 1 (brain)
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPA1 pyrophosphatase (inorganic) 1
PRUNE2 prune homolog 2 (Drosophila)
PTTG1 pituitary tumor-transforming 1
RND3 Rho family GTPase 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TBCB tubulin folding cofactor B
TKT transketolase
TRIB3 tribbles pseudokinase 3
TSPAN4 tetraspanin 4
TYMS thymidylate synthetase
ZFP36L1 ZFP36 ring finger protein-like 1