BRD-A06784547_MRS 1334_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

164 genes differentially expressed following the BRD-A06784547_MRS 1334_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AMIGO2 adhesion molecule with Ig-like domain 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCR2 chemokine (C-C motif) receptor 2
CD8A CD8a molecule
CD93 CD93 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
COL15A1 collagen, type XV, alpha 1
COL4A5 collagen, type IV, alpha 5
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSZ cathepsin Z
DPYD dihydropyrimidine dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENO1 enolase 1, (alpha)
ERAP2 endoplasmic reticulum aminopeptidase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FGF13 fibroblast growth factor 13
FOXF1 forkhead box F1
GNLY granulysin
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
IL2RG interleukin 2 receptor, gamma
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT18 keratin 18, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAGEB2 melanoma antigen family B2
MEIS2 Meis homeobox 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NELL2 NEL-like 2 (chicken)
NRGN neurogranin (protein kinase C substrate, RC3)
PAX6 paired box 6
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL2 phospholipase C-like 2
PRKCQ protein kinase C, theta
PSPH phosphoserine phosphatase
PTPRC protein tyrosine phosphatase, receptor type, C
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCAN2 regulator of calcineurin 2
RGS16 regulator of G-protein signaling 16
RPP38 ribonuclease P/MRP 38kDa subunit
SFRP1 secreted frizzled-related protein 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SOX2 SRY (sex determining region Y)-box 2
TFF1 trefoil factor 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLR4 toll-like receptor 4
TRAC T cell receptor alpha constant
TRBC1 T cell receptor beta constant 1
TRIB1 tribbles pseudokinase 1
TRPS1 trichorhinophalangeal syndrome I
TSPAN6 tetraspanin 6
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACTN1 actinin, alpha 1
ADGRE5 adhesion G protein-coupled receptor E5
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
AREG amphiregulin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAMLG calcium modulating ligand
CCDC6 coiled-coil domain containing 6
CCND3 cyclin D3
CD59 CD59 molecule, complement regulatory protein
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CENPU centromere protein U
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC5 chloride intracellular channel 5
CSRP1 cysteine and glycine-rich protein 1
CTSL cathepsin L
CYB5A cytochrome b5 type A (microsomal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP10 dual specificity phosphatase 10
EBP emopamil binding protein (sterol isomerase)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5 eukaryotic translation initiation factor 5
ELN elastin
EMX2 empty spiracles homeobox 2
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
GDF15 growth differentiation factor 15
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLS glutaminase
HBB hemoglobin, beta
HEBP1 heme binding protein 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP4 insulin-like growth factor binding protein 4
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAG1 jagged 1
KAZN kazrin, periplakin interacting protein
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD12 potassium channel tetramerization domain containing 12
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDM5D lysine (K)-specific demethylase 5D
KIAA0226L KIAA0226-like
KRT14 keratin 14, type I
LAMC1 laminin, gamma 1 (formerly LAMB2)
LDLR low density lipoprotein receptor
LOXL1 lysyl oxidase-like 1
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
MMP7 matrix metallopeptidase 7
MSLN mesothelin
MSMO1 methylsterol monooxygenase 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NRIP3 nuclear receptor interacting protein 3
OXTR oxytocin receptor
PCM1 pericentriolar material 1
PCOLCE procollagen C-endopeptidase enhancer
PHF20 PHD finger protein 20
PON2 paraoxonase 2
PPA1 pyrophosphatase (inorganic) 1
PRR7 proline rich 7 (synaptic)
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RAB13 RAB13, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RHOQ ras homolog family member Q
RPIA ribose 5-phosphate isomerase A
RPS4Y1 ribosomal protein S4, Y-linked 1
RWDD1 RWD domain containing 1
SACS sacsin molecular chaperone
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SF1 splicing factor 1
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX6 sorting nexin 6
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SYBU syntabulin (syntaxin-interacting)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFRC transferrin receptor
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNIP1 TNFAIP3 interacting protein 1
TNPO1 transportin 1
TRAK2 trafficking protein, kinesin binding 2
TSPAN3 tetraspanin 3
TSPYL5 TSPY-like 5
UGCG UDP-glucose ceramide glucosyltransferase
UROD uroporphyrinogen decarboxylase