BRD-A06784547_MRS 1334_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-A06784547_MRS 1334_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDK6 cyclin-dependent kinase 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL10A1 collagen, type X, alpha 1
CRISP3 cysteine-rich secretory protein 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
FABP4 fatty acid binding protein 4, adipocyte
FAM171A1 family with sequence similarity 171, member A1
FRY furry homolog (Drosophila)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT23 keratin 23, type I
LSR lipolysis stimulated lipoprotein receptor
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAGEB2 melanoma antigen family B2
PRTN3 proteinase 3
SERTAD2 SERTA domain containing 2
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SRGN serglycin
SST somatostatin
TFF3 trefoil factor 3 (intestinal)
TMEM110 transmembrane protein 110

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADI1 acireductone dioxygenase 1
AKAP1 A kinase (PRKA) anchor protein 1
ANXA5 annexin A5
ASPH aspartate beta-hydroxylase
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BIN1 bridging integrator 1
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CCNA2 cyclin A2
CD14 CD14 molecule
CD163 CD163 molecule
CD52 CD52 molecule
CERS6 ceramide synthase 6
CHN1 chimerin 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FCGBP Fc fragment of IgG binding protein
FGG fibrinogen gamma chain
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPRC5B G protein-coupled receptor, class C, group 5, member B
HRSP12 heat-responsive protein 12
IGHM immunoglobulin heavy constant mu
KIAA0226L KIAA0226-like
MAOA monoamine oxidase A
MTF2 metal response element binding transcription factor 2
MYBPC1 myosin binding protein C, slow type
MYCBP MYC binding protein
NRCAM neuronal cell adhesion molecule
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
NUP85 nucleoporin 85kDa
RBP4 retinol binding protein 4, plasma
RNASE6 ribonuclease, RNase A family, k6
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SNRPE small nuclear ribonucleoprotein polypeptide E
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STAB1 stabilin 1
TFPI2 tissue factor pathway inhibitor 2
TPST2 tyrosylprotein sulfotransferase 2
TRIP6 thyroid hormone receptor interactor 6
VLDLR very low density lipoprotein receptor
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF395 zinc finger protein 395