BRD-A06390036_HYDROQUINIDINE_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A06390036_HYDROQUINIDINE_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACTN1 actinin, alpha 1
ADM adrenomedullin
C8ORF4 chromosome 8 open reading frame 4
CFI complement factor I
CPT1A carnitine palmitoyltransferase 1A (liver)
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GLDC glycine dehydrogenase (decarboxylating)
GMDS GDP-mannose 4,6-dehydratase
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
LOC100505650 uncharacterized LOC100505650
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MPO myeloperoxidase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PGD phosphogluconate dehydrogenase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
SCG5 secretogranin V
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP29 Rho GTPase activating protein 29
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GUSBP11 glucuronidase, beta pseudogene 11
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
MBP myelin basic protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP12 matrix metallopeptidase 12
MZB1 marginal zone B and B1 cell-specific protein
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PID1 phosphotyrosine interaction domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon