BRD-A06352508_SB 218078_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A06352508_SB 218078_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADO 2-aminoethanethiol (cysteamine) dioxygenase
BMP2 bone morphogenetic protein 2
CCL2 chemokine (C-C motif) ligand 2
CCL8 chemokine (C-C motif) ligand 8
CCND1 cyclin D1
CCND2 cyclin D2
CD14 CD14 molecule
CXCL13 chemokine (C-X-C motif) ligand 13
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HBEGF heparin-binding EGF-like growth factor
IL17RB interleukin 17 receptor B
MT1F metallothionein 1F
PAGE4 P antigen family, member 4 (prostate associated)
PRR7 proline rich 7 (synaptic)
PTN pleiotrophin
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
SIRPA signal-regulatory protein alpha
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM43 transmembrane protein 43
TSPAN4 tetraspanin 4
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BASP1 brain abundant, membrane attached signal protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
BRCA1 breast cancer 1, early onset
CBR3 carbonyl reductase 3
CDK19 cyclin-dependent kinase 19
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CPM carboxypeptidase M
DEFB1 defensin, beta 1
DLK1 delta-like 1 homolog (Drosophila)
DUSP5 dual specificity phosphatase 5
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FOXD1 forkhead box D1
FOXO3 forkhead box O3
GDF15 growth differentiation factor 15
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB7 homeobox B7
IL7R interleukin 7 receptor
KLK11 kallikrein-related peptidase 11
KRT1 keratin 1, type II
MDK midkine (neurite growth-promoting factor 2)
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPTX2 neuronal pentraxin II
NTS neurotensin
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIR pirin (iron-binding nuclear protein)
PKM pyruvate kinase, muscle
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN2 perilipin 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RANBP9 RAN binding protein 9
RHCG Rh family, C glycoprotein
SPDEF SAM pointed domain containing ETS transcription factor
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM50A transmembrane protein 50A
TMSB15A thymosin beta 15a
TUBB2A tubulin, beta 2A class IIa
UGCG UDP-glucose ceramide glucosyltransferase