BRD-A06352508_SB 218078_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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64 genes differentially expressed following the BRD-A06352508_SB 218078_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AREG amphiregulin
C3 complement component 3
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
CYBRD1 cytochrome b reductase 1
DACH1 dachshund family transcription factor 1
EREG epiregulin
ESR1 estrogen receptor 1
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
HLA-B major histocompatibility complex, class I, B
HOPX HOP homeobox
KRT19 keratin 19, type I
METRN meteorin, glial cell differentiation regulator
MFAP5 microfibrillar associated protein 5
MSLN mesothelin
MXRA5 matrix-remodelling associated 5
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SATB2 SATB homeobox 2
SPON1 spondin 1, extracellular matrix protein
TRIM2 tripartite motif containing 2
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAM10 ADAM metallopeptidase domain 10
ADRB2 adrenoceptor beta 2, surface
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BLCAP bladder cancer associated protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CD58 CD58 molecule
CDC25B cell division cycle 25B
CHN2 chimerin 2
CTSH cathepsin H
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
FAM13A family with sequence similarity 13, member A
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
IL1B interleukin 1, beta
ITGA6 integrin, alpha 6
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NAV3 neuron navigator 3
NRN1 neuritin 1
P3H2 prolyl 3-hydroxylase 2
PLA2G16 phospholipase A2, group XVI
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PXDN peroxidasin
RASA1 RAS p21 protein activator (GTPase activating protein) 1
REXO2 RNA exonuclease 2
SPC25 SPC25, NDC80 kinetochore complex component
TBC1D4 TBC1 domain family, member 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM97 transmembrane protein 97
TXNRD1 thioredoxin reductase 1