BRD-A06352508_SB 218078_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-A06352508_SB 218078_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BIRC2 baculoviral IAP repeat containing 2
BPHL biphenyl hydrolase-like (serine hydrolase)
CARS cysteinyl-tRNA synthetase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD24 CD24 molecule
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP3 dual specificity phosphatase 3
GAL galanin/GMAP prepropeptide
HBB hemoglobin, beta
HIST1H2AC histone cluster 1, H2ac
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
LRPPRC leucine-rich pentatricopeptide repeat containing
NMU neuromedin U
ORC1 origin recognition complex, subunit 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RET ret proto-oncogene
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
RPL10 ribosomal protein L10
RSRP1 arginine/serine-rich protein 1
SF1 splicing factor 1
SMC1A structural maintenance of chromosomes 1A
SOX9 SRY (sex determining region Y)-box 9
SRSF7 serine/arginine-rich splicing factor 7
TUBB2A tubulin, beta 2A class IIa
XIST X inactive specific transcript (non-protein coding)
ZFP36 ZFP36 ring finger protein
ZNF593 zinc finger protein 593

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AMIGO2 adhesion molecule with Ig-like domain 2
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD99 CD99 molecule
COL6A1 collagen, type VI, alpha 1
COTL1 coactosin-like F-actin binding protein 1
CPD carboxypeptidase D
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLC1 DLC1 Rho GTPase activating protein
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETV1 ets variant 1
FKBP1A FK506 binding protein 1A, 12kDa
HEG1 heart development protein with EGF-like domains 1
HMGA2 high mobility group AT-hook 2
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KDM5D lysine (K)-specific demethylase 5D
KYNU kynureninase
LAMA3 laminin, alpha 3
LIMA1 LIM domain and actin binding 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LOX lysyl oxidase
MAOA monoamine oxidase A
MLPH melanophilin
MMP1 matrix metallopeptidase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
PFN2 profilin 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRSS23 protease, serine, 23
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOBP sine oculis binding protein homolog (Drosophila)
STC1 stanniocalcin 1
SULF1 sulfatase 1
TF transferrin
TIMP3 TIMP metallopeptidase inhibitor 3
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WNT5A wingless-type MMTV integration site family, member 5A