BRD-A06352508_SB 218078_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-A06352508_SB 218078_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ASS1 argininosuccinate synthase 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPCAM epithelial cell adhesion molecule
FAM129A family with sequence similarity 129, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KCTD5 potassium channel tetramerization domain containing 5
LOC100505650 uncharacterized LOC100505650
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP7 matrix metallopeptidase 7
MT1M metallothionein 1M
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NELL2 NEL-like 2 (chicken)
PEG3 paternally expressed 3
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
QPCT glutaminyl-peptide cyclotransferase
RHOBTB3 Rho-related BTB domain containing 3
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQSTM1 sequestosome 1
TF transferrin
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AUTS2 autism susceptibility candidate 2
CALD1 caldesmon 1
CCNA2 cyclin A2
CCNB2 cyclin B2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CENPF centromere protein F, 350/400kDa
CHEK2 checkpoint kinase 2
CRABP2 cellular retinoic acid binding protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELOVL6 ELOVL fatty acid elongase 6
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPHA3 EPH receptor A3
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD7 frizzled class receptor 7
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
MEIS1 Meis homeobox 1
METRN meteorin, glial cell differentiation regulator
MFAP2 microfibrillar-associated protein 2
MRPS16 mitochondrial ribosomal protein S16
MSMO1 methylsterol monooxygenase 1
NCK2 NCK adaptor protein 2
PRSS23 protease, serine, 23
RAB31 RAB31, member RAS oncogene family
SEPT11 septin 11
SRI sorcin
STMN1 stathmin 1
TCF4 transcription factor 4
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa
ZNF22 zinc finger protein 22
ZNF395 zinc finger protein 395