BRD-A06352508_SB 218078_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-A06352508_SB 218078_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BEX4 brain expressed, X-linked 4
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
CP ceruloplasmin (ferroxidase)
DEFB1 defensin, beta 1
EFNB2 ephrin-B2
EGR1 early growth response 1
EREG epiregulin
ESR1 estrogen receptor 1
G0S2 G0/G1 switch 2
GEM GTP binding protein overexpressed in skeletal muscle
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
KRT23 keratin 23, type I
LOC100505650 uncharacterized LOC100505650
MRPS2 mitochondrial ribosomal protein S2
MYLK myosin light chain kinase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
ORM1 orosomucoid 1
PITX1 paired-like homeodomain 1
PLS1 plastin 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRO protein tyrosine phosphatase, receptor type, O
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RRAGD Ras-related GTP binding D
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOX9 SRY (sex determining region Y)-box 9
TBX2 T-box 2
TDO2 tryptophan 2,3-dioxygenase
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
ALCAM activated leukocyte cell adhesion molecule
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATRX alpha thalassemia/mental retardation syndrome X-linked
BASP1 brain abundant, membrane attached signal protein 1
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHN2 chimerin 2
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DENND1B DENN/MADD domain containing 1B
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EFNA1 ephrin-A1
ETV1 ets variant 1
FBN1 fibrillin 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HES1 hes family bHLH transcription factor 1
HOXA5 homeobox A5
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
KIF14 kinesin family member 14
KTN1 kinectin 1 (kinesin receptor)
LAT2 linker for activation of T cells family, member 2
LIMCH1 LIM and calponin homology domains 1
LRRC16A leucine rich repeat containing 16A
LYZ lysozyme
MDFIC MyoD family inhibitor domain containing
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PON2 paraoxonase 2
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RGS1 regulator of G-protein signaling 1
RHOBTB3 Rho-related BTB domain containing 3
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPHS1 selenophosphate synthetase 1
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TARP TCR gamma alternate reading frame protein
TBX3 T-box 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGIF1 TGFB-induced factor homeobox 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAK2 trafficking protein, kinesin binding 2
UGDH UDP-glucose 6-dehydrogenase
WIF1 WNT inhibitory factor 1
WNT5A wingless-type MMTV integration site family, member 5A