BRD-A06352508_SB 218078_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

114 genes differentially expressed following the BRD-A06352508_SB 218078_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ANXA3 annexin A3
ASCL1 achaete-scute family bHLH transcription factor 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHERP calcium homeostasis endoplasmic reticulum protein
CNPY3 canopy FGF signaling regulator 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDB2 damage-specific DNA binding protein 2, 48kDa
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP3 dual specificity phosphatase 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPCAM epithelial cell adhesion molecule
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GNPDA1 glucosamine-6-phosphate deaminase 1
HBEGF heparin-binding EGF-like growth factor
HIST1H2BG histone cluster 1, H2bg
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
INPP1 inositol polyphosphate-1-phosphatase
KLF10 Kruppel-like factor 10
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCSK1 proprotein convertase subtilisin/kexin type 1
PGLS 6-phosphogluconolactonase
PRR7 proline rich 7 (synaptic)
RAB31 RAB31, member RAS oncogene family
RFX5 regulatory factor X, 5 (influences HLA class II expression)
S100A12 S100 calcium binding protein A12
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOX9 SRY (sex determining region Y)-box 9
SSFA2 sperm specific antigen 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPP1 tripeptidyl peptidase I
VAT1 vesicle amine transport 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AUTS2 autism susceptibility candidate 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
CA12 carbonic anhydrase XII
CD99 CD99 molecule
CDC45 cell division cycle 45
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CENPU centromere protein U
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
COL6A2 collagen, type VI, alpha 2
COLEC12 collectin sub-family member 12
CSRP2 cysteine and glycine-rich protein 2
CYB5A cytochrome b5 type A (microsomal)
DCN decorin
DERA deoxyribose-phosphate aldolase (putative)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBLN1 fibulin 1
FBN1 fibrillin 1
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FN1 fibronectin 1
FSTL1 follistatin-like 1
GAS1 growth arrest-specific 1
HOPX HOP homeobox
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IQGAP2 IQ motif containing GTPase activating protein 2
ITM2A integral membrane protein 2A
LAMA4 laminin, alpha 4
LBH limb bud and heart development
LRRC17 leucine rich repeat containing 17
LY96 lymphocyte antigen 96
MPC2 mitochondrial pyruvate carrier 2
MX1 MX dynamin-like GTPase 1
MYBPC1 myosin binding protein C, slow type
NID2 nidogen 2 (osteonidogen)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRL platelet-derived growth factor receptor-like
PEG3 paternally expressed 3
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAP1GAP RAP1 GTPase activating protein
SOBP sine oculis binding protein homolog (Drosophila)
SOX11 SRY (sex determining region Y)-box 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRED2 sprouty-related, EVH1 domain containing 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STMN1 stathmin 1
SULF1 sulfatase 1
TCF4 transcription factor 4
TF transferrin
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TPM1 tropomyosin 1 (alpha)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WNT5A wingless-type MMTV integration site family, member 5A
ZEB1 zinc finger E-box binding homeobox 1