BRD-A06352418_TERFENADINE_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

76 genes differentially expressed following the BRD-A06352418_TERFENADINE_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
ANXA4 annexin A4
ARHGAP29 Rho GTPase activating protein 29
ARMCX1 armadillo repeat containing, X-linked 1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASS1 argininosuccinate synthase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
CDC25B cell division cycle 25B
CLEC7A C-type lectin domain family 7, member A
CLNS1A chloride channel, nucleotide-sensitive, 1A
DDIT3 DNA-damage-inducible transcript 3
DHCR7 7-dehydrocholesterol reductase
DPP4 dipeptidyl-peptidase 4
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGFR2 fibroblast growth factor receptor 2
FTH1 ferritin, heavy polypeptide 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MARCKS myristoylated alanine-rich protein kinase C substrate
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDZK1IP1 PDZK1 interacting protein 1
PFKM phosphofructokinase, muscle
PLIN2 perilipin 2
PRKX protein kinase, X-linked
PTPRK protein tyrosine phosphatase, receptor type, K
RND3 Rho family GTPase 3
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SFRP1 secreted frizzled-related protein 1
SLC38A2 solute carrier family 38, member 2
SQLE squalene epoxidase
TBX3 T-box 3
TKT transketolase
TNNT1 troponin T type 1 (skeletal, slow)
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CNN1 calponin 1, basic, smooth muscle
DLD dihydrolipoamide dehydrogenase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ITGA6 integrin, alpha 6
KIF14 kinesin family member 14
MYH11 myosin, heavy chain 11, smooth muscle
NEFL neurofilament, light polypeptide
PDE4D phosphodiesterase 4D, cAMP-specific
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMEPA1 prostate transmembrane protein, androgen induced 1
PMP22 peripheral myelin protein 22
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPIA ribose 5-phosphate isomerase A
S100P S100 calcium binding protein P
SATB2 SATB homeobox 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TGM2 transglutaminase 2