BRD-A06276885_N-Benzylnaltrindole hydrochloride_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A06276885_N-Benzylnaltrindole hydrochloride_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CAPN2 calpain 2, (m/II) large subunit
CST1 cystatin SN
DDIT4 DNA-damage-inducible transcript 4
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LGALS4 lectin, galactoside-binding, soluble, 4
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOX4 SRY (sex determining region Y)-box 4
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TM4SF4 transmembrane 4 L six family member 4
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCDC47 coiled-coil domain containing 47
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
DLD dihydrolipoamide dehydrogenase
GNG10 guanine nucleotide binding protein (G protein), gamma 10
HES1 hes family bHLH transcription factor 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MAN1C1 mannosidase, alpha, class 1C, member 1
MXRA5 matrix-remodelling associated 5
NRIP1 nuclear receptor interacting protein 1
PLS3 plastin 3
STOM stomatin
TSPAN13 tetraspanin 13