BRD-A06276885_N-Benzylnaltrindole hydrochloride_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-A06276885_N-Benzylnaltrindole hydrochloride_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
CPA3 carboxypeptidase A3 (mast cell)
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KCNK1 potassium channel, two pore domain subfamily K, member 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
NPTX2 neuronal pentraxin II
NT5DC2 5'-nucleotidase domain containing 2
POU2AF1 POU class 2 associating factor 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
TACSTD2 tumor-associated calcium signal transducer 2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TXNIP thioredoxin interacting protein
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ASPN asporin
CCL20 chemokine (C-C motif) ligand 20
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
HBB hemoglobin, beta
RPS5 ribosomal protein S5
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28