BRD-A06276885_N-Benzylnaltrindole hydrochloride_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

83 genes differentially expressed following the BRD-A06276885_N-Benzylnaltrindole hydrochloride_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX1 armadillo repeat containing, X-linked 1
ASS1 argininosuccinate synthase 1
CD36 CD36 molecule (thrombospondin receptor)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CECR1 cat eye syndrome chromosome region, candidate 1
CLDN3 claudin 3
DLK1 delta-like 1 homolog (Drosophila)
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FGFR1 fibroblast growth factor receptor 1
FTH1 ferritin, heavy polypeptide 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GLUL glutamate-ammonia ligase
GSE1 Gse1 coiled-coil protein
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
KRT19 keratin 19, type I
LCN2 lipocalin 2
MAGEA3 melanoma antigen family A3
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
NMU neuromedin U
NPC1 Niemann-Pick disease, type C1
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SQLE squalene epoxidase
STAB1 stabilin 1
TDO2 tryptophan 2,3-dioxygenase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein
VSIG4 V-set and immunoglobulin domain containing 4
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CDC42 cell division cycle 42
CIAPIN1 cytokine induced apoptosis inhibitor 1
CST1 cystatin SN
CXCL8 chemokine (C-X-C motif) ligand 8
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EIF5 eukaryotic translation initiation factor 5
FAM57A family with sequence similarity 57, member A
FGF2 fibroblast growth factor 2 (basic)
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
ISG15 ISG15 ubiquitin-like modifier
KRT10 keratin 10, type I
KRT7 keratin 7, type II
MOK MOK protein kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
REEP5 receptor accessory protein 5
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS4 regulator of G-protein signaling 4
S100A10 S100 calcium binding protein A10
S100A6 S100 calcium binding protein A6
STOM stomatin
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOX3 TOX high mobility group box family member 3
TPM4 tropomyosin 4
UBE2S ubiquitin-conjugating enzyme E2S
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon