BRD-A06276885_N-Benzylnaltrindole hydrochloride_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-A06276885_N-Benzylnaltrindole hydrochloride_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANXA5 annexin A5
COL9A3 collagen, type IX, alpha 3
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYSL2 dihydropyrimidinase-like 2
FABP7 fatty acid binding protein 7, brain
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP5 insulin-like growth factor binding protein 5
IGKV4-1 immunoglobulin kappa variable 4-1
LDLR low density lipoprotein receptor
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MGP matrix Gla protein
MSMO1 methylsterol monooxygenase 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PNMA2 paraneoplastic Ma antigen 2
RET ret proto-oncogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDCBP syndecan binding protein (syntenin)
SOX9 SRY (sex determining region Y)-box 9
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
STX1A syntaxin 1A (brain)
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
BCL2A1 BCL2-related protein A1
HBB hemoglobin, beta
MAOA monoamine oxidase A
S100A8 S100 calcium binding protein A8
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
TFPI2 tissue factor pathway inhibitor 2