BRD-A05680309_MLS-0390982_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A05680309_MLS-0390982_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AHSG alpha-2-HS-glycoprotein
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA7 annexin A7
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
C5 complement component 5
CCL2 chemokine (C-C motif) ligand 2
CFB complement factor B
CHI3L2 chitinase 3-like 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FABP1 fatty acid binding protein 1, liver
FGL1 fibrinogen-like 1
GCLM glutamate-cysteine ligase, modifier subunit
HPX hemopexin
IGHMBP2 immunoglobulin mu binding protein 2
IL32 interleukin 32
INHBA inhibin, beta A
ISG15 ISG15 ubiquitin-like modifier
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MT1E metallothionein 1E
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MYB v-myb avian myeloblastosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORM1 orosomucoid 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
PPARG peroxisome proliferator-activated receptor gamma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100P S100 calcium binding protein P
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SOD2 superoxide dismutase 2, mitochondrial
STC1 stanniocalcin 1
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
AHNAK2 AHNAK nucleoprotein 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C1QA complement component 1, q subcomponent, A chain
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRABP2 cellular retinoic acid binding protein 2
CRYAB crystallin, alpha B
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
FGF9 fibroblast growth factor 9
FZD2 frizzled class receptor 2
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
GPX3 glutathione peroxidase 3
GRN granulin
GSN gelsolin
GSTA4 glutathione S-transferase alpha 4
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBB hemoglobin, beta
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KCTD12 potassium channel tetramerization domain containing 12
NEFL neurofilament, light polypeptide
NT5DC2 5'-nucleotidase domain containing 2
NUPR1 nuclear protein, transcriptional regulator, 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PFKM phosphofructokinase, muscle
PLXNC1 plexin C1
REEP1 receptor accessory protein 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STMN2 stathmin 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
ZMYND8 zinc finger, MYND-type containing 8