BRD-A05680309_MLS-0390982_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A05680309_MLS-0390982_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
C8ORF4 chromosome 8 open reading frame 4
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CFB complement factor B
CPA3 carboxypeptidase A3 (mast cell)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
E2F5 E2F transcription factor 5, p130-binding
ERAP1 endoplasmic reticulum aminopeptidase 1
IFI27 interferon, alpha-inducible protein 27
L1CAM L1 cell adhesion molecule
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
OPTN optineurin
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTX3 pentraxin 3, long
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SULF1 sulfatase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TESK1 testis-specific kinase 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
CAPN3 calpain 3, (p94)
CD24 CD24 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYBA cytochrome b-245, alpha polypeptide
DCN decorin
DSP desmoplakin
FGFR3 fibroblast growth factor receptor 3
GADD45B growth arrest and DNA-damage-inducible, beta
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSN gelsolin
HOPX HOP homeobox
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
LCN2 lipocalin 2
LMO2 LIM domain only 2 (rhombotin-like 1)
NEFL neurofilament, light polypeptide
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G16 phospholipase A2, group XVI
PTCH1 patched 1
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SFTPC surfactant protein C
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCTA T-cell leukemia translocation altered
TGM2 transglutaminase 2
TPD52L1 tumor protein D52-like 1