BRD-A05680309_MLS-0390982_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A05680309_MLS-0390982_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIRC3 baculoviral IAP repeat containing 3
CCL2 chemokine (C-C motif) ligand 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
DLK1 delta-like 1 homolog (Drosophila)
EFHD2 EF-hand domain family, member D2
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
NAV3 neuron navigator 3
NCAM1 neural cell adhesion molecule 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDE4B phosphodiesterase 4B, cAMP-specific
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMS spermine synthase
SPRY4 sprouty homolog 4 (Drosophila)
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3

decreased expression

Symbol Name
AK4 adenylate kinase 4
CAT catalase
CDA cytidine deaminase
CFD complement factor D (adipsin)
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
COX5B cytochrome c oxidase subunit Vb
CXADR coxsackie virus and adenovirus receptor
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
FADS1 fatty acid desaturase 1
FBP1 fructose-1,6-bisphosphatase 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
HOXB6 homeobox B6
IGFBP5 insulin-like growth factor binding protein 5
ITGB1BP1 integrin beta 1 binding protein 1
KRT18 keratin 18, type I
PEG3 paternally expressed 3
PNMA2 paraneoplastic Ma antigen 2
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
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